Document Detail


The central role of Bcl-3 in atopic dermatitis.
MedLine Citation:
PMID:  19809421     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cytokines and hormones are essential mediators in the regulation of antimicrobial peptide and protein (AMP) levels during host defense responses. In this issue, Büchau et al. identify and characterize B-cell leukemia-3 as an important modulator of AMP expression during the innate immune response in keratinocytes as well as in the chronic inflammatory skin disorder atopic dermatitis.
Authors:
Ramin Massoumi
Publication Detail:
Type:  Comment; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  129     ISSN:  1523-1747     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-10-07     Completed Date:  2009-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2088-90     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine, Lund University, Malmö University Hospital, Malmö, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Antimicrobial Cationic Peptides / genetics,  physiology
Dermatitis, Atopic / etiology*,  immunology,  therapy
Humans
Immunity, Innate
Keratinocytes / immunology
Proto-Oncogene Proteins / physiology*
Transcription Factors / physiology*
Vitamin D / administration & dosage
Chemical
Reg. No./Substance:
0/Antimicrobial Cationic Peptides; 0/Proto-Oncogene Proteins; 0/Transcription Factors; 0/proto-oncogene protein bcl-3; 1406-16-2/Vitamin D; 143108-26-3/CAP18 lipopolysaccharide-binding protein
Comments/Corrections
Comment On:
J Invest Dermatol. 2009 Sep;129(9):2148-55   [PMID:  19282837 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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