Document Detail


The cell biology of fertilization.
MedLine Citation:
PMID:  9361807     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Research into the cell biology of mammalian fertilization has been stimulated by the desire to provide a theoretical framework for the development of novel approaches to contraception and the need to understand the cellular basis of human infertility. The results of such studies have revealed a complex cascade of interactions initiated by the contact between capacitated spermatozoa on the oocyte-cumulus complex and culminating in sperm-oocyte fusion. In this review we shall examine our current understanding of the fertilization process, highlighting the strategic importance of recent findings and key areas where information is lacking.
Authors:
R J Aitken
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  424     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  1997  
Date Detail:
Created Date:  1998-01-20     Completed Date:  1998-01-20     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  291-9     Citation Subset:  IM    
Affiliation:
MRC Reproductive Biology Unit, Centre for Reproductive Biology, Edinburgh, Scotland.
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MeSH Terms
Descriptor/Qualifier:
Animals
Fertilization / physiology*
Humans
Male
Sperm Capacitation / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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