Document Detail

A case with euprolactinemic galactorrhea induced by escitalopram.
MedLine Citation:
PMID:  18314855     Owner:  NLM     Status:  MEDLINE    
Endocrine and reproductive side effects of serotonergic antidepressants are uncommon and galactorrhea is only rarely mentioned among SSRI-related side effects. Perhaps through suppression of dopamine neurotransmission releasing prolactin from tonic inhibitor control of dopamine, serotonin-enhancing antidepressants may result in a rise in prolactin levels. However, we here describe a case of euprolactinemic galactorrhea induced by the SSRI escitalopram and discuss potential mechanisms of action.
Murat Gulsun; Ayhan Algul; Umit Basar Semiz; Mehmet Alpay Ates; Ali Doruk; Servet Ebrinc; Cengiz Basoglu; Mesut Cetin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of psychiatry in medicine     Volume:  37     ISSN:  0091-2174     ISO Abbreviation:  Int J Psychiatry Med     Publication Date:  2007  
Date Detail:
Created Date:  2008-03-04     Completed Date:  2008-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365646     Medline TA:  Int J Psychiatry Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  275-8     Citation Subset:  IM    
Isparta Military Hospital, Psychiatry Service, Turkey.
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MeSH Terms
Citalopram / adverse effects*,  therapeutic use
Drug Administration Schedule
Galactorrhea / blood,  chemically induced*,  epidemiology
Hyperprolactinemia / epidemiology
Panic Disorder / blood,  drug therapy*
Prolactin / blood*
Serotonin Uptake Inhibitors / adverse effects*,  therapeutic use
Reg. No./Substance:
0/Serotonin Uptake Inhibitors; 59729-33-8/Citalopram; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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