| A case of virilizing adrenocortical carcinoma. | |
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MedLine Citation:
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PMID: 2834927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 36-year-old woman who had experienced two pregnancies consulted our hospital, because of scant menses and virilization. A 24-hour excretion of 17-ketosteroids and 17-hydroxy-corticosteroids demonstrated a decrease in 11-hydroxylase. A computed tomogram showed a huge inhomogenous tumefaction in the left adrenal. Left selective renal angiography revealed a large adrenal tumefaction. Selective adrenal venous samplings revealed that testosterone and dehydroepiandrosterone (DHA) were produced in response to stimulation by 0.25 mg exogenous adrenocorticotropic hormone (ACTH). After left adrenalectomy was performed, a diagnosis of adrenocortical carcinoma was made by pathological examination. This is the first report of a patient with a virilizing adrenocortical carcinoma, which produced testosterone and DHA in response to exogenous ACTH stimulation. |
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Authors:
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H Takiuchi; T Oka; M Namiki; Y Ichikawa; T Sonoda; M Koga; B Sato; S Onishi; T Nakamura; H Matsushita |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Hinyokika kiyo. Acta urologica Japonica Volume: 33 ISSN: 0018-1994 ISO Abbreviation: Hinyokika Kiyo Publication Date: 1987 Dec |
Date Detail:
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Created Date: 1988-06-07 Completed Date: 1988-06-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0421145 Medline TA: Hinyokika Kiyo Country: JAPAN |
Other Details:
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Languages: eng Pagination: 2090-4 Citation Subset: IM |
Affiliation:
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Department of Urology, Osaka University Hospital. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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17-Hydroxycorticosteroids
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urine 17-Ketosteroids / urine Adrenal Cortex Neoplasms / diagnosis*, pathology Adrenocorticotropic Hormone / diagnostic use Adult Carcinoma / diagnosis*, pathology Dehydroepiandrosterone / blood Female Humans Testosterone / blood Tomography, X-Ray Computed Virilism* |
| Chemical | |
Reg. No./Substance:
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0/17-Hydroxycorticosteroids; 0/17-Ketosteroids; 53-43-0/Dehydroepiandrosterone; 58-22-0/Testosterone; 9002-60-2/Adrenocorticotropic Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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