Document Detail


A case of trisomy 22 in Pongo pygmaeus.
MedLine Citation:
PMID:  88305     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A behaviorally and clinically abnormal female orangutan was analyzed cytologically using general banding techniques and by an alkaline silver method for staining nucleolus organizer regions. The karyotype had 49 chromosomes, including an extra chromosome 22 (49,XX + 22). No variant chromosome types or heterozygous structural rearrangements were found. Nine of the 14 large acrocentric chromosomes, Nos. 11--17, and three of the five presumptive human G-group equivalents, i.e., two of three chromosomes 22, and one chromosome from pair 23, exhibited positive silver staining of the nucleolus organizer region (NOR).
Authors:
M Andrle; W Fiedler; A Rett; P Ambros; D Schweizer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  24     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  1979  
Date Detail:
Created Date:  1979-09-17     Completed Date:  1979-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Nucleolus / ultrastructure
Female
Hominidae / genetics*
Karyotyping
Silver / diagnostic use
Staining and Labeling
Trisomy*
Chemical
Reg. No./Substance:
7440-22-4/Silver

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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