Document Detail


A case of tracheobronchitis in ulcerative colitis: a review of literature.
MedLine Citation:
PMID:  20298372     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Tracheobronchitis is a rare extraintestinal manifestation of ulcerative colitis (UC) and is often mis-diagnosed and treated as asthma. OBJECTIVE: We report a case of tracheobromchitis in a patient with long-standing UC, who had been treated for asthma for many years with a poor response to standard asthma management. Only very few cases are reported and in the majority of them tracheobronchitis developed after colectomy. Methods: Subsequent investigations of unremitting respiratory symptoms in our patient revealed tracheobronchitis. His UC remained quiescent for more than 20 years on medical treatment having never required a bowel resection. RESULTS: On thoroughly investigating the aetiology for his pulmonary pathology, it was thought to be an extraintestinal manifestation of UC, which makes this case noteworthy. CONCLUSION: Pulmonary complications can develop many years after the diagnosis of inflammatory bowel disease, without any sign of disease activity. In such cases awareness and a high index of suspicion are important to ensure early diagnosis and treatment, and further investigations to detect large airway disease is warranted. The pulmonary manifestations tend to respond well to steroid therapy, which may prevent or ameliorate permanent lung damage.
Authors:
Soma Kar; S G Thomas
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The clinical respiratory journal     Volume:  3     ISSN:  1752-699X     ISO Abbreviation:  Clin Respir J     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2010-03-19     Completed Date:  2010-06-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101315570     Medline TA:  Clin Respir J     Country:  England    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  IM    
Affiliation:
Department of Respiratory Medicine, Calderdale Royal Hospital, Halifax, West Yorkshire, UK. drsomakar@hotmail.co.uk
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MeSH Terms
Descriptor/Qualifier:
Azathioprine / administration & dosage
Biopsy, Needle
Bronchitis / complications*,  diagnosis*,  drug therapy
Bronchoscopy / methods
Colitis, Ulcerative / complications*,  diagnosis,  therapy
Drug Therapy, Combination
Follow-Up Studies
Humans
Immunohistochemistry
Male
Middle Aged
Prednisolone / administration & dosage
Rare Diseases
Respiratory Mucosa / pathology
Risk Assessment
Tomography, X-Ray Computed
Tracheitis / complications*,  diagnosis*,  drug therapy
Treatment Outcome
Chemical
Reg. No./Substance:
446-86-6/Azathioprine; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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