Document Detail

A case of thyrotoxicosis and reversible systolic cardiac dysfunction.
MedLine Citation:
PMID:  10411619     Owner:  NLM     Status:  MEDLINE    
A woman with congestive heart failure and reduced left ventricular ejection fraction associated with hyperthyroidism is reported. Congestive heart failure resolved and left ventricular ejection fraction normalized within three weeks of treatment of her hyperthyroidism. The literature on previously reported cases of reversible systolic heart failure associated with hyperthyroidism is reviewed and the possible mechanisms leading to systolic dysfunction and congestive heart failure in thyrotoxicosis are discussed. One such mechanism may be the action of thyroid hormone on altering gene expression in cardiac cells; another could be the chronic tachycardia associated with thyrotoxicosis. Although it is a not a common cause of systolic heart failure, thyrotoxicosis should be considered in the differential diagnosis of cardiomyopathies because it is a potentially reversible cause.
L E Goldman; D J Sahlas; M Sami
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  15     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-08-04     Completed Date:  1999-08-04     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  811-4     Citation Subset:  IM    
Royal Victoria Hospital, McGill University, Montreal, Canada.
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MeSH Terms
Arrhythmia, Sinus
Cardiomyopathy, Dilated / complications*,  radiography
Heart Failure / complications*,  radiography
Middle Aged
Radiography, Thoracic
Tachycardia, Ventricular / diagnosis
Thyrotoxicosis / complications*
Ventricular Dysfunction, Left

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