| A case of small round cell tumor of the thoracopulmonary region with myogenic and neurogenic elements. | |
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MedLine Citation:
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PMID: 1580155 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We here report a unique case of a young boy with an intrathoracic tumor which consisted of neurogenic and myogenic elements. The initial pathological diagnosis was alveolar rhabdomyosarcoma. The tumor tissue from surgical resection was composed of three parts, each showing a different histological appearance, i.e. a monotonous small cell area, an alveolar area, and an area consisting of pleomorphic rhabdomyoblasts. The small round cells in the monotonous area were immunoreactive with the antibodies for Leu7, neuron-specific enolase (NSE), neurofilament proteins (NFP), and beta 2 microglobulin, but not with the antibody for desmin. These cells also had dense core granules. The tumor cells in the alveolar area were immunoreactive with the antibodies for Leu7 and desmin, but not with the antibody for NFP. Pleomorphic rhabdomyoblasts were immunoreactive with the antibody for desmin, but not with the antibodies for Leu7 and NFP. These findings imply that this tumor consisted of neurogenic and myogenic elements and is considered to be a special type of rhabdomyosarcoma. |
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Authors:
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J Goji; K Sano; R Murakami; H Nakamura; M Ninomiya; H Ito |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta paediatrica Japonica; Overseas edition Volume: 34 ISSN: 0374-5600 ISO Abbreviation: Acta Paediatr Jpn Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1992-06-09 Completed Date: 1992-06-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370357 Medline TA: Acta Paediatr Jpn Country: JAPAN |
Other Details:
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Languages: eng Pagination: 65-71 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Kobe University School of Medicine, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal Child Desmin / analysis Humans Immunohistochemistry Male Neurofilament Proteins / analysis Phosphopyruvate Hydratase / analysis Rhabdomyosarcoma / diagnosis*, ultrastructure Thoracic Neoplasms / diagnosis*, ultrastructure Tumor Markers, Biological / analysis |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Desmin; 0/Neurofilament Proteins; 0/Tumor Markers, Biological; EC 4.2.1.11/Phosphopyruvate Hydratase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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