| A case of severe staphylococcal septicaemia: septic arthritis and a mediastinal abscess following leflunamide therapy for rheumatoid arthritis. | |
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MedLine Citation:
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PMID: 22766573 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This highly unusual case illustrates how a potentially life-threatening complication may develop insidiously in the context of immunosuppression. A 46-year-old woman presented with increasing malaise and a marked inflammatory response in the context of immunosuppressive therapy for rhueumatoid arthritis. On the basis of microbiological findings, the patient was treated for systemic staphylococcal infection with a prolonged antibiotic course. In addition, incision and drainage procedures were performed on associated, non-resolving abscesses at various sites. One particular lesion in the breast was slow to heal and was monitored with ultrasound imaging. Subsequent cross-sectional imaging revealed that this was, in fact, a large mediastinal abscess, eroding the manubrium and lying within close proximity of the aorta. The patient was eventually referred to a cardiothoracic unit for complete evacuation of this lesion. Following a prolonged illness and treatment period, the patient recovered well and successfully resumed employment. |
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Authors:
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Anjali Balasanthiran; Tannaz Vakilgilani; Ken Darzy; Jeremy Axon |
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Publication Detail:
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Type: Journal Article Date: 2010-08-19 |
Journal Detail:
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Title: BMJ case reports Volume: 2010 ISSN: 1757-790X ISO Abbreviation: BMJ Case Rep Publication Date: 2010 |
Date Detail:
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Created Date: 2012-07-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101526291 Medline TA: BMJ Case Rep Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: IM |
Affiliation:
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Specialist Registrar in Diabetes and Endocrinology, Lister Hospital, Coreys Mill Lane, Stevenage, Hertfordshire, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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