| A case of severe ARDS caused by novel swine-origin influenza (A/H1N1pdm) virus: a successful treatment with direct hemoperfusion with polymyxin B-immobilized fiber. | |
| | |
MedLine Citation:
|
PMID: 20623785 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
In 2009, a 35-year-old female with Down syndrome was admitted to our hospital because of severe pneumonia caused by an infection with the novel swine-origin influenza (A/H1N1pdm) virus (S-OIV). A chest X-ray on admission revealed bilateral infiltration shadows. Although mechanical ventilation was administered because of the development of ARDS, the hypoxemia continued to progressed. We observed evidence of alveolar hemorrhage on evaluation of the patient using bronchofiberscopy. The bacterial examination was negative. Despite intensive care, including respiratory management with high-frequency oscillatory ventilation (HFOV), the patient's hypoxemia and hypotension progressed. We concluded that a cytokine storm due to the influenza infection with SIRS caused shock status, resulting in septic shock. We subsequently treated the patient with direct hemoperfusion with polymyxin B-immobilized fiber (PMX-DHP). The hypoxemia improved immediately. She was free from mechanical ventilation and discharged from the hospital by the 17th day of her hospitalization. PMX-DHP seems to improve hypoxemia in patients with severe ARDS who cannot maintain sufficient respiratory control under mechanical ventilation. This case is the first report about severe and life-threatening ARDS due to the novel influenza, in which PMX-DHP showed beneficial effects. |
| | |
Authors:
|
Toshiki Yokoyama; Kazunari Tateishi; Kenji Tsushima; Toshihiko Agatsuma; Hiroshi Yamamoto; Tomonobu Koizumi; Keishi Kubo |
Related Documents
:
|
2415085 - The influence of norakin on the reproduction of influenza a and b viruses. 13651915 - The effect of a previous attack of a1 influenza on susceptibility to a2 virus during th... 11234975 - Zanamivir: a rational approach to influenza b. 20938815 - Novel swine--origin influenza a: the 2009 h1n1 influenza virus. 22329815 - Discrimination of influenza a subtype by antibodies recognizing host-specific amino aci... 15220425 - Direct evidence for natural transmission of small-ruminant lentiviruses of subtype a4 f... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of clinical apheresis Volume: 25 ISSN: 1098-1101 ISO Abbreviation: J Clin Apher Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-12-07 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8216305 Medline TA: J Clin Apher Country: United States |
Other Details:
|
Languages: eng Pagination: 350-3 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Wiley-Liss, Inc. |
Affiliation:
|
First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Rinseback during red blood cell exchange with COBE Spectra does not affect fraction of cells remaini...
Next Document: High rates of tumor growth and disease progression detected on serial pretreatment fluorodeoxyglucos...