Document Detail

A case series of prosthetic heart valve thrombosis-derived coronary embolism.
MedLine Citation:
PMID:  25080955     Owner:  NLM     Status:  Publisher    
Coronary thromboembolism is a rare cause of acute coronary syndromes (ACS). The information regarding ACS in patients with prosthetic heart valves is scarce and based mainly on case reports. Although plaque rupture is the most common cause of acute myocardial infarction, coronary embolism (CE) is not a rare cause of acute myocardial infarction. There is no consensus regarding the treatment in such a situation. We present three cases of prosthetic valve thrombosis complicated with CE causing non-ST elevation ACS, who were successfully treated with thrombolytic therapy (TT). We administered low-dose (25 mg), slow-infusion (6 hours) tissue plasminogen activator (t-PA), which was shown to be safe and effective in our group in a large study. The patients benefited from TT with respect to the coronary flow, as shown by the lysis of thrombi in all three patients on coronary angiogram.
Süleyman Karakoyun; Mustafa Ozan Gürsoy; Macit Kalçık; Mahmut Yesin; Mehmet Ozkan
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Publication Detail:
Journal Detail:
Title:  Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir     Volume:  42     ISSN:  1016-5169     ISO Abbreviation:  Turk Kardiyol Dern Ars     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-8-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9426239     Medline TA:  Turk Kardiyol Dern Ars     Country:  -    
Other Details:
Languages:  ENG     Pagination:  467-471     Citation Subset:  -    
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