Document Detail

A case series of gastrointestinal abnormalities in fetuses with echogenic bowel detected during the antenatal period.
MedLine Citation:
PMID:  14626795     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The objective was to evaluate the incidence of gastrointestinal abnormalities amongst those fetuses with antenatally diagnosed echogenic bowel (EB). MATERIALS AND METHODS: A retrospective review of all cases delivered from April 2002 to March 2003 with antenatally diagnosed EB was conducted. This was defined as bowel that appeared as echogenic as (if not greater than) the iliac bone on a real-time image. The postnatal outcomes with regard to gastrointestinal abnormalities, till their discharge, were noted. RESULTS: Of the 13,941 patients delivered, there were 70 cases with antenatally diagnosed EB, giving an incidence of 70/13,941 or 0.50%. Of these, 6 defaulted follow-up and 1 had a mid-trimester termination of pregnancy at 21 weeks' gestation for social reasons. Of the remaining 63 cases with EB, 2 were stillbirths at 31 weeks and 35 weeks of gestation, respectively. Three fetuses (3/63 or 4.76%) were diagnosed with gastrointestinal abnormalities. Meconium plug syndrome was diagnosed postnatally in 2 cases, of which, 1 resolved with conservative management while the other required an emergency laparotomy. Intestinal atresia was diagnosed in the postmortem of one of the stillbirths. There was evidence of intrauterine growth retardation (IUGR) in both the stillbirth and the fetus that had required laparotomy. None of the 3 fetuses exhibited clinical features of aneuploidy. CONCLUSION: As the quoted background risk for gastrointestinal pathology is 0.23%, an increased incidence (4.76%) is observed in those fetuses found to have antenatal EB. It is possible that the presence of IUGR is associated with a worse prognosis. Further prospective studies are needed to verify this association.
H H Tan; V C Tan; G S Yeo
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  32     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-11-20     Completed Date:  2004-03-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  649-52     Citation Subset:  IM    
Department of Maternal Fetal Medicine, KK Women's & Children's Hospital, 100 Bukit Timah Road, Singapore 229899.
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MeSH Terms
Abnormalities, Multiple / epidemiology,  ultrasonography
Fetal Diseases / epidemiology*,  ultrasonography
Fetal Growth Retardation / epidemiology*,  ultrasonography
Infant, Newborn
Intestinal Obstruction / epidemiology*,  ultrasonography
Intestines / abnormalities*
Maternal Age
Meconium / ultrasonography
Pregnancy Outcome*
Pregnancy Trimester, Second
Pregnancy, High-Risk
Prenatal Care / methods
Risk Factors
Singapore / epidemiology
Ultrasonography, Prenatal

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