Document Detail

A case of sensorineural deafness following ingestion of sildenafil.
MedLine Citation:
PMID:  17166328     Owner:  NLM     Status:  MEDLINE    
We report a case of bilateral profound unremitting sensorineural hearing loss, in a 44-year-old male patient occurring after ingestion of sildenafil citrate 50 mg/day for 15 days. Audiological evaluation documented the findings. Sildenafil is an effective oral treatment for erectile dysfunction syndrome. It is being used and abused by many people as availability is easy and it can even be bought over the internet. Many patients are unaware of the harmful effects of sildenafil and take the drug without medical supervision. We could not find any previously reported cases of sildenafil induced hearing loss and to the best of our knowledge, this is the first case report of sildenafil induced sensorineural hearing loss in the world literature.
B Mukherjee; T Shivakumar
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-12-14
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  121     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-03     Completed Date:  2007-08-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  395-7     Citation Subset:  AIM; IM    
Department of Otorhinolaryngology, Command Hospital Air Force, Bangalore, India.
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MeSH Terms
Erectile Dysfunction / drug therapy*
Hearing Loss, Sensorineural / chemically induced*
Phosphodiesterase Inhibitors / adverse effects*
Piperazines / adverse effects*
Purines / adverse effects
Sulfones / adverse effects*
Reg. No./Substance:
0/Phosphodiesterase Inhibitors; 0/Piperazines; 0/Purines; 0/Sulfones; 139755-83-2/sildenafil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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