Document Detail


A case report of subacute thyroiditis during pregnancy: difficulties in differential diagnosis and changes in cytokine levels.
MedLine Citation:
PMID:  20528573     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Introduction. Thyroid dysfunction during pregnancy may result in both maternal and neonatal complications. Subacute thyroiditis (SAT) is an extremely rare cause of both hyper- and hypothyroidism in pregnant women. Case description. A case of first trimester SAT is presented. Diagnosis of SAT was based on fine-needle aspiration biopsy. The disease resolved spontaneously without need for prednisone administration but a hypothyroid phase treated with T4 throughout pregnancy occurred. The pregnancy resulted in a healthy full term infant. We measured various cytokine levels in an attempt to follow their course during SAT as well as throughout the remaining period of pregnancy. Serum thyreoglobulin (Tg) levels correlated best with thyroid function tests (TFTs) and the course of SAT. Conclusions. The diagnosis of SAT at a pregnancy setting may be intriguing. The measurement of circulating cytokines is not helpful in the differential diagnosis or monitoring of the disease.
Authors:
Athanasios D Anastasilakis; Vassiliki Karanicola; Anargyros Kourtis; Polyzois Makras; Lampros Kampas; Spyridon Gerou; Athina Giomisi
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Publication Detail:
Type:  Journal Article     Date:  2010-06-09
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  27     ISSN:  1473-0766     ISO Abbreviation:  Gynecol. Endocrinol.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  384-90     Citation Subset:  IM    
Affiliation:
Department of Endocrinology, 424 Military Hospital, Thessaloniki, Greece.
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