Document Detail

A case report of massive vulvar edema during tocolysis of preterm labor.
MedLine Citation:
PMID:  1872351     Owner:  NLM     Status:  MEDLINE    
Bilateral vulvar edema that is not associated with preeclampsia has been reported only rarely during pregnancy or the puerperium. A primiparous patient in premature labor at 34 weeks' gestation with no history of lymphatic or venous obstruction underwent combination tocolysis with intravenous ritodrine and magnesium sulfate. On the fifth day of tocolysis, edema developed in the right labium majus pudendi and gradually spread to the left labia during the ensuing 24 hours. The patient remained afebrile, normotensive, and without signs of localized infection or anasarca. A trial of triple intravenous antibiotics and local skin care proved ineffective. By the ninth hospital day, the edema and discomfort had progressed, thereby precluding vaginal examination without sedation. In spite of progressive cervical dilatation with tocolysis, cesarean delivery was performed. With no further treatment, the vulvar edema gradually resolved during the next week.
C Brittain; J W Carlson; D L Gehlbach; A W Robertson
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  165     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-09-16     Completed Date:  1991-09-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  420-2     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, William Beaumont Army Medical Center, El Paso, TX 79920-5001.
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MeSH Terms
Clindamycin / therapeutic use
Edema / chemically induced*,  drug therapy
Gentamicins / therapeutic use
Magnesium Sulfate / adverse effects
Nafcillin / therapeutic use
Pregnancy Trimester, Third
Tocolysis / adverse effects*
Vulvar Diseases / chemically induced*,  drug therapy
Reg. No./Substance:
0/Gentamicins; 147-52-4/Nafcillin; 18323-44-9/Clindamycin; 7487-88-9/Magnesium Sulfate

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