Document Detail

A case of relapsing polychondritis preceded by inner ear involvement.
MedLine Citation:
PMID:  15882830     Owner:  NLM     Status:  MEDLINE    
Relapsing polychondritis is a rare disease of unknown etiology causing systematic inflammation of the whole cartilaginous tissues. We report a patient with relapsing polychondritis preceded by inner ear involvement. A 68-year-old female visited our hospital for a chief complaint of sudden bilateral hearing loss. On pure-tone audiometry, sensorineural hearing loss, 47dB on the right and 51dB on the left, was observed. Later, bilateral auricular chondritis and uveitis developed. On biopsy of the auricular cartilage, perichondritis was observed. The patient was diagnosed with relapsing polychondritis in the early stage, 2 weeks after the onset. Oral predonine administration was initiated, and the auricular inflammation was improved within 10 days. The hearing loss disorder was gradually improved. The steroid dose was reduced, and no decrease in hearing has been observed so far.
Kenichi Kumakiri; Taiko Sakamoto; Taro Karahashi; Hiroyuki Mineta; Satoru Takebayashi
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-11-24
Journal Detail:
Title:  Auris, nasus, larynx     Volume:  32     ISSN:  0385-8146     ISO Abbreviation:  Auris Nasus Larynx     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-05-10     Completed Date:  2005-09-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7708170     Medline TA:  Auris Nasus Larynx     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  71-6     Citation Subset:  IM    
Department of Otorhinolaryngology, Fujieda Municipal General Hospital, 4-1-11 Surugadai, Fujieda, Shizuoka 426-8677, Japan.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Anti-Inflammatory Agents / therapeutic use
Audiometry, Pure-Tone / methods
Ear, Inner / pathology*
Hearing Loss, Sensorineural / diagnosis,  etiology
Polychondritis, Relapsing / complications*,  drug therapy,  pathology*
Prednisolone / therapeutic use
Severity of Illness Index
Uveitis / complications*,  drug therapy,  pathology
Vitamin B 12 / analogs & derivatives,  therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Inflammatory Agents; 13422-55-4/mecobalamin; 50-24-8/Prednisolone; 68-19-9/Vitamin B 12

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