Document Detail

A case of rapid deterioration in sperm quality following spinal cord injury.
MedLine Citation:
PMID:  16010279     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: Case report.
SETTING: Northwest Regional Spinal Injuries Unit, Southport, UK and Reproductive Medicine Unit, Liverpool Women's Hospital, Liverpool, UK.
CASE REPORT: A 28-year-old man suffered from paraplegia on sustaining a fall. Fertility preservation was an important aspect of his treatment and electro-ejaculation and cryopreservation of sperm was possible within days of sustaining the fall. The sperm samples obtained subsequently showed a rapid decline in quality. Frozen sperm from the first normal ejaculate obtained soon after the injury was used for assisted reproduction and has resulted in an ongoing pregnancy.
CONCLUSION: This case highlights the importance of collection and freezing of seminal fluid within 2 weeks of spinal cord injury (SCI), or earlier to improve fertility outcomes in spinal cord-injured men, as the clinical stability of the patient may allow.
S Das; B M Soni; S D Sharma; R Gazvani; D I Lewis-Jones
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Spinal cord     Volume:  44     ISSN:  1362-4393     ISO Abbreviation:  Spinal Cord     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-06     Completed Date:  2006-04-26     Revised Date:  2011-06-06    
Medline Journal Info:
Nlm Unique ID:  9609749     Medline TA:  Spinal Cord     Country:  England    
Other Details:
Languages:  eng     Pagination:  56-8     Citation Subset:  IM    
Hewitt Centre for Reproductive Medicine, Liverpool Women's Hospital, Liverpool, UK.
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MeSH Terms
Cryopreservation / methods
Fertilization in Vitro
Infertility, Male / etiology*,  physiopathology
Paraplegia / complications,  physiopathology
Semen / cytology,  physiology*
Semen Preservation / methods
Spermatozoa / pathology,  physiology*
Spinal Cord Injuries / complications*,  physiopathology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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