Document Detail


A case of pulmonary intravascular lymphomatosis diagnosed by thoracoscopic lung biopsy.
MedLine Citation:
PMID:  14512679     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intravascular lymphomatosis with primary pulmonary lesion is an extremely rare disease. Although the major clinical symptoms include fever, cough, dyspnea and loss of body weight, these are not diagnostic. Chest radiograph findings are also nonspecific and include bilateral reticular shadow, reticulonodular shadow, ground-glass opacity or wedge-shaped subpleural opacities. Therefore, the antemortem diagnosis is relatively difficult. It is considered that intravascular lymphomatosis is a high-grade malignant lymphoma. However, it has been shown recently that a good response and long-term survival may possibly be obtained through systemic combination chemotherapy. We report a case of intravascular lymphomatosis with primary pulmonary lesion where an early diagnosis was obtained through thoracoscopic lung biopsy and subsequent systemic chemotherapy proved to be quite effective. Because the clinical symptoms or chest radiograph findings are usually nonspecific, it was thought that thoracoscopic lung biopsy could be a useful procedure for early and reliable diagnosis of primary pulmonary intravascular lymphomatosis and that it might contribute to an improved prognosis.
Authors:
Toshiyuki Yamagata; Yukiharu Okamoto; Kiichiro Ota; Norifumi Katayama; Tadaaki Tsuda; Susumu Yukawa
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  70     ISSN:  0025-7931     ISO Abbreviation:  Respiration     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-09-26     Completed Date:  2004-01-20     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  414-8     Citation Subset:  IM    
Copyright Information:
Copyright 2003 S. Karger AG, Basel
Affiliation:
Division of Clinical Oncology and Palliative Medicine, Wakayama Medical University, Wakayama, Japan. y-toshi@wakayama-med.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Humans
Lung / pathology*,  radiography
Lymphoma / drug therapy,  pathology*,  radiography
Male
Pulmonary Circulation*
Radiography, Thoracic
Thoracoscopy*
Tomography, X-Ray Computed
Vascular Neoplasms / drug therapy,  pathology*,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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