Document Detail


A case of propofol-induced oropharyngeal angioedema and bronchospasm.
MedLine Citation:
PMID:  22211170     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Propofol (2,6-diisopropylphenol) is an ultrashort-acting sedative agent with sedative and amnestic effects that is used not only for anesthesia but also for sedation during minor outpatient procedures and endoscopic examinations. Rare cases of anaphylaxis following propofol administration have been reported in the medical literature. Documentation of anaphylaxis is often lacking because the cause and effect relationship is often hard to prove. Only a minority of patients get referred for allergy testing to confirm the offending drug. Here we report a 74-year-old woman who had an anaphylactic reaction with severe oropharyngeal edema and bronchospasm for a few minutes after receiving propofol during endoscopic examination. An allergy skin test was positive for both propofol and soybean. Soybean in the intralipid is one component of propofol, and we concluded that this anaphylaxis was caused by soybean.
Authors:
Byung-Chul You; An-Soo Jang; Ji-Su Han; Hong-Woo Cheon; Jong-Suk Park; June-Hyuk Lee; Sung-Woo Park; Do-Jin Kim; Choon-Sik Park
Publication Detail:
Type:  Journal Article     Date:  2011-11-18
Journal Detail:
Title:  Allergy, asthma & immunology research     Volume:  4     ISSN:  2092-7363     ISO Abbreviation:  Allergy Asthma Immunol Res     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-01-02     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101518382     Medline TA:  Allergy Asthma Immunol Res     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  46-8     Citation Subset:  -    
Affiliation:
Division of Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
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