| A case of progressive hypertension preceding gemcitabine-associated thrombotic microangiopathy complicated by acute kidney injury and stroke. | |
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MedLine Citation:
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PMID: 19814643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Gemcitabine-associated thrombotic microangiopathy is being increasingly recognized as a serious complication of treatment. We report a normotensive patient who developed progressive hypertension after commencing gemcitabine therapy. She also developed subtle changes in her platelet count and serum creatinine months before her emergent presentation. Clinicians should be aware of new onset or worsening hypertension and 'mild' biochemical changes in gemcitabine-treated patients. |
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Authors:
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Paul J Phelan; Aaron Liew; Colm Magee |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Renal failure Volume: 31 ISSN: 1525-6049 ISO Abbreviation: Ren Fail Publication Date: 2009 |
Date Detail:
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Created Date: 2009-10-09 Completed Date: 2010-01-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8701128 Medline TA: Ren Fail Country: England |
Other Details:
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Languages: eng Pagination: 743-4 Citation Subset: IM |
Affiliation:
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Department of Nephrology, Beaumont Hospital, Dublin 9, Ireland. paulphel@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antineoplastic Agents / adverse effects* Deoxycytidine / adverse effects, analogs & derivatives* Disease Progression Female Humans Hypertension / chemically induced* Kidney Failure, Acute / etiology* Pancreatic Neoplasms / drug therapy*, surgery Stroke / etiology* Thrombotic Microangiopathies / chemically induced* |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 103882-84-4/gemcitabine; 951-77-9/Deoxycytidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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