Document Detail


A case of progressive hypertension preceding gemcitabine-associated thrombotic microangiopathy complicated by acute kidney injury and stroke.
MedLine Citation:
PMID:  19814643     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gemcitabine-associated thrombotic microangiopathy is being increasingly recognized as a serious complication of treatment. We report a normotensive patient who developed progressive hypertension after commencing gemcitabine therapy. She also developed subtle changes in her platelet count and serum creatinine months before her emergent presentation. Clinicians should be aware of new onset or worsening hypertension and 'mild' biochemical changes in gemcitabine-treated patients.
Authors:
Paul J Phelan; Aaron Liew; Colm Magee
Related Documents :
17468993 - Efficacy and safety of nifedipine gits in chinese patients with hypertension--a post-ma...
22413 - The sympathetic system in hypertension.
8322043 - Linguistic characteristics of neurotic, borderline and psychotic personality organization.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Renal failure     Volume:  31     ISSN:  1525-6049     ISO Abbreviation:  Ren Fail     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-09     Completed Date:  2010-01-05     Revised Date:  2013-06-03    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  England    
Other Details:
Languages:  eng     Pagination:  743-4     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Beaumont Hospital, Dublin 9, Ireland. paulphel@gmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acute Kidney Injury / etiology*
Aged
Antineoplastic Agents / adverse effects*
Deoxycytidine / adverse effects,  analogs & derivatives*
Disease Progression
Female
Humans
Hypertension / chemically induced*
Pancreatic Neoplasms / drug therapy*,  surgery
Stroke / etiology*
Thrombotic Microangiopathies / chemically induced*
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 951-77-9/Deoxycytidine; B76N6SBZ8R/gemcitabine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Preserved residual kidney function after twelve years' hemodialysis.
Next Document:  Hydralazine-induced ANCA-positive pauci-immune glomerulonephritis: a case report and literature revi...