| A case of primary ovarian lymphoma with autoimmune hemolytic anemia achieving complete response with Rituximab-based combination chemotherapy. | |
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MedLine Citation:
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PMID: 22563154 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Ovarian involvement as primary or secondary lymphomatous process is extremely uncommon. In most cases, the diagnosis is usually not suspected initially and is confirmed only after detailed histopathological evaluation. We report a patient with primary ovarian diffuse large B-cell lymphoma (DLBCL) and associated auto-immune hemolytic anemia (AIHA) who achieved complete remission after treatment with Rituximab-cyclophosphamide-doxorubicin-vincristine and prednisolone (R-CHOP) chemotherapy. This patient was a 50 year old female, who presented with fever, abdominal pain, vomiting, weight loss and anemia. Computed tomography scan of the abdomen and pelvis revealed a large left ovarian mass with bilateral hydronephrosis. We performed exploratory laparotomy and partial resection of the mass was done due to the adhesions. Histopathology confirmed the diagnosis of DLBCL. After six R-CHOP chemotherapy cycles, patient achieved complete response with correction of anemia. To our knowledge, this may be the first case report till date of primary ovarian DLBCL with AIHA treated with R-CHOP chemotherapy who achieved complete remission in terms of primary disease as well as hemolytic anemia. |
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Authors:
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N S Ghadyalpatil; R Chandrasekar; D Snehalatha; B M Reddy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology Volume: 32 ISSN: 0975-2129 ISO Abbreviation: Indian J Med Paediatr Oncol Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2012-05-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9604571 Medline TA: Indian J Med Paediatr Oncol Country: India |
Other Details:
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Languages: eng Pagination: 207-10 Citation Subset: - |
Affiliation:
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Department of Medical Oncology, Yashoda Hospital, Hyderabad, Andhra Pradesh, India. |
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