| A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature. | |
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MedLine Citation:
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PMID: 17135744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm. CASE REPORT: A 79-year-old man presented with a 3-cm nodular tumor of the left leg occurring on a primary chronic lymphedema of the legs. The lesion was CD56+, CD3 intracytoplasmic+, CD45+ and Epstein-Barr virus+. A comprehensive workup including CT scan and bone marrow biopsy was negative and a diagnosis of NKTL-NT with a primary cutaneous involvement was made. The patient was free of disease under multi-agent chemotherapy after 24 months of follow-up. DISCUSSION: After reviewing 18 other cases of primary cutaneous NKTL-NT, we conclude that the prognosis of these lymphomas is usually poor. However, limited cutaneous forms have a longer median survival than extracutaneous variants. |
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Authors:
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J Stokkermans-Dubois; T Jouary; B Vergier; M M Delaunay; A Taieb |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Dermatology (Basel, Switzerland) Volume: 213 ISSN: 1018-8665 ISO Abbreviation: Dermatology (Basel) Publication Date: 2006 |
Date Detail:
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Created Date: 2006-11-30 Completed Date: 2007-02-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203244 Medline TA: Dermatology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 345-9 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2006 S. Karger AG, Basel. |
Affiliation:
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Skin and Cancer Unit, Department of Dermatology, Saint André Hospital, Bordeaux, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antigens, CD45 / analysis Antigens, CD56 / analysis Antineoplastic Combined Chemotherapy Protocols / therapeutic use Follow-Up Studies Humans Killer Cells, Natural / pathology* Leg Lymphedema / diagnosis Lymphoma, T-Cell, Cutaneous / diagnosis*, pathology Male Skin Neoplasms / diagnosis*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD56; EC 3.1.3.48/Antigens, CD45 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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