Document Detail


A case of portal vein thrombosis after laparoscopy-assisted splenectomy and cholecystectomy in a child.
MedLine Citation:
PMID:  17706514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of an 8-year-old boy with a red cell membrane disorder who developed, soon after undergoing laparoscopic cholecystectomy and splenectomy, complete thrombosis of the right branch and a partial occlusion of the left branch of the portal vein. The child was affected by a right hemiparesis because of a hypoxic-ischemic disorder that occurred in the first hours of life and was heterozygous for the methylenetetrahydrofolate reductase gene mutation 677C-T. Intravenous heparin and aspirin were initiated on postoperative day 7. Heparin treatment was switched to the subcutaneous route after the first 24 hours. The symptoms subsided 3 days after the beginning of treatment, whereas complete resolution of portal vein thrombosis was observed 2 months later. A review of the literature is reported, and the possible pathogenetic mechanisms underlying portal vein thrombosis are discussed.
Authors:
Enrica Rossi; Maria Elena Michelini; Caterina Borgna Pignatti; Fausto Zanotti; Andrea Franchella
Related Documents :
3568954 - Intrahepatic cholestasis of pregnancy with marked elevation of transaminases in a black...
10023764 - Radial forearm fasciocutaneous free flap as a solution in case of noma.
16418964 - Gastroschisis and biliary atresia in a neonate: uncommon presentation or common precipi...
24811304 - Chronic dialysis discontinuation: a systematic narrative review of the literature in th...
9218034 - Adrenal insufficiency from bilateral adrenal hemorrhage after total knee replacement su...
457114 - Partial trisomy 4q: two cases with a familial translocation t(4;18)(q27;q23).
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  42     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-20     Completed Date:  2007-09-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1449-51     Citation Subset:  IM    
Affiliation:
Operative Unit of Pediatric Surgery, Arcispedale S. Anna, 44100 Ferrara, Italy. dr_ross28@hotmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anemia, Hemolytic, Congenital / surgery*
Anticoagulants / administration & dosage*
Aspirin / administration & dosage
Child
Cholecystectomy, Laparoscopic / adverse effects*
Heparin / administration & dosage
Humans
Laparoscopy
Male
Methylenetetrahydrofolate Reductase (NADPH2) / genetics
Mutation
Portal Vein*
Splenectomy / adverse effects*
Venous Thrombosis / etiology*,  therapy
Chemical
Reg. No./Substance:
0/Anticoagulants; 50-78-2/Aspirin; 9005-49-6/Heparin; EC 1.5.1.20/Methylenetetrahydrofolate Reductase (NADPH2)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Concurrent imperforate hymen, transverse vaginal septum, and unicornuate uterus: a case report.
Next Document:  Carney's triad: a 16-year follow-up.