| A case of portal vein thrombosis after laparoscopy-assisted splenectomy and cholecystectomy in a child. | |
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MedLine Citation:
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PMID: 17706514 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of an 8-year-old boy with a red cell membrane disorder who developed, soon after undergoing laparoscopic cholecystectomy and splenectomy, complete thrombosis of the right branch and a partial occlusion of the left branch of the portal vein. The child was affected by a right hemiparesis because of a hypoxic-ischemic disorder that occurred in the first hours of life and was heterozygous for the methylenetetrahydrofolate reductase gene mutation 677C-T. Intravenous heparin and aspirin were initiated on postoperative day 7. Heparin treatment was switched to the subcutaneous route after the first 24 hours. The symptoms subsided 3 days after the beginning of treatment, whereas complete resolution of portal vein thrombosis was observed 2 months later. A review of the literature is reported, and the possible pathogenetic mechanisms underlying portal vein thrombosis are discussed. |
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Authors:
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Enrica Rossi; Maria Elena Michelini; Caterina Borgna Pignatti; Fausto Zanotti; Andrea Franchella |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 42 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-08-20 Completed Date: 2007-09-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1449-51 Citation Subset: IM |
Affiliation:
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Operative Unit of Pediatric Surgery, Arcispedale S. Anna, 44100 Ferrara, Italy. dr_ross28@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic, Congenital
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surgery* Anticoagulants / administration & dosage* Aspirin / administration & dosage Child Cholecystectomy, Laparoscopic / adverse effects* Heparin / administration & dosage Humans Laparoscopy Male Methylenetetrahydrofolate Reductase (NADPH2) / genetics Mutation Portal Vein* Splenectomy / adverse effects* Venous Thrombosis / etiology*, therapy |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 50-78-2/Aspirin; 9005-49-6/Heparin; EC 1.5.1.20/Methylenetetrahydrofolate Reductase (NADPH2) |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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