Document Detail

A case of portal vein arterialization after a liver transplant.
MedLine Citation:
PMID:  23767946     Owner:  NLM     Status:  In-Data-Review    
Hepatic artery thrombosis represents a potentially deadly complication after a liver transplant. Portal vein arterialization recently has been proposed as a bridge approach in patients with hepatic artery thrombosis needing a retransplant. We report the case of a 53-year-old man treated with a liver transplant for a cryptogenetic cirrhosis. One month after a liver transplant, a hepatic artery thrombosis was documented, and a portal vein arterialization as bridge therapy for another liver transplant was performed. After surgery, improvement in the patient's liver functioning was seen. No signs of portal hypertension or hepatic abscesses were documented. Unfortunately, 8 months after the liver transplant, the patient experienced a severe urinary infection caused by a multidrug-resistant Klebsiella and died. An increase in the oxygen supply to the liver parenchyma after portal vein arterializations represents rationale use for managing hepatic artery thromboses. Several cases of treating post liver transplant hepatic artery thromboses have been reported in the literature. Portal vein arterializations can be used as bridge therapy in well-selected situations of post-liver transplant hepatic artery thromboses. Strict surveillance should be used to prevent the onset of complications that can exclude a patient from a transplant. The correct timing for retransplant is not fully known, but we think the shorter the time to retransplant, the better is the patient survival.
Fabio Melandro; Quirino Lai; Giovanni B Levi Sandri; Nicola Guglielmo; Marco Di Laudo; Vincenzo Morabito; Renzo Pretagostini; Pasquale B Berloco; Massimo Rossi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation     Volume:  11     ISSN:  2146-8427     ISO Abbreviation:  Exp Clin Transplant     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-06-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101207333     Medline TA:  Exp Clin Transplant     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  287-9     Citation Subset:  IM    
Department of General Surgery and Organ Transplantation, Sapienza University, Umberto I Hospital, Rome, Italy.
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