Document Detail

A case of platypnea-orthodeoxia syndrome caused by the interaction between the presence of corrected transposition of the great arteries and patent foramen ovale.
MedLine Citation:
PMID:  18706706     Owner:  NLM     Status:  MEDLINE    
A 42-year-old was admitted to our institution for recurrent episodic dyspnea on exertion. The patient had also a history of recurrent transient ischemic attacks. Careful history taking revealed that she developed dyspnea in an upright position, whereas the symptoms were relieved in a supine position (platypnea). The patient was given the diagnosis of platypnea-orthodeoxia syndrome. Transthoracic echocardiography showed cardiac situs solitus levocardia with great artery transposition with intact interventricular septum, patent foramen ovale (PFO) and moderate right atrial dilatation. Agitated saline contrast injection demonstrated the presence of spontaneous right-to-left shunt. The patient underwent transcatheter closure of PFO. After percutaneous closure of PFO patient became asymptomatic and hypoxemia induced by orthostatic conditions did not appear again. A transthoracic echocardiography performed after two months, showed the complete closure of PFO, without residual shunt.
G Gasparini; M Rossi; D Zavalloni; G Belli; P Pagnotta; V Lisignoli; C Barbaro; A Lanzone; P Presbitero
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Publication Detail:
Type:  Case Reports; Letter     Date:  2008-08-15
Journal Detail:
Title:  International journal of cardiology     Volume:  138     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-02-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e1-3     Citation Subset:  IM    
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MeSH Terms
Anoxia / etiology
Dyspnea / etiology*
Foramen Ovale, Patent / complications*,  radiography,  ultrasonography
Supine Position
Tomography, X-Ray Computed
Transposition of Great Vessels / complications*,  radiography,  ultrasonography

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