Document Detail


A case of ochronosis with gout and Monckeberg arteries.
MedLine Citation:
PMID:  19247659     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Alkaptonuria is an inborn error of amino acid metabolism. A defect in tyrosine metabolism that results in accumulation of homogentisic acid in connective tissue, especially cartilage, has long been known. Degenerative arthropathy, especially of the knee and spine, develops at a relatively early age in adults. Accumulation also occurs in heart valves, and there may be a predisposition to atherosclerosis. We describe a 72-year-old man with ochronosis, gouty arthritis of both hands, and monckeberg arteries.
Authors:
Hadi Karimzadeh; Negin Mohtasham; Mansoor Karimifar; Mansour Salesi; Zahra Sayed Bonakdar
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-02-27
Journal Detail:
Title:  Rheumatology international     Volume:  29     ISSN:  1437-160X     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-08-19     Completed Date:  2010-02-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1507-10     Citation Subset:  IM    
Affiliation:
Rheumatology Department, Isfahan University for Medical Sciences, Alzahra Hospital, Isfahan, Iran. Karimzadeh@Med.mui.ac.ir
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MeSH Terms
Descriptor/Qualifier:
Aged
Allopurinol / therapeutic use
Anti-Inflammatory Agents / therapeutic use
Gout / diagnosis*,  drug therapy,  etiology*
Gout Suppressants / therapeutic use
Hand / radiography
Humans
Male
Monckeberg Medial Calcific Sclerosis / diagnosis*,  drug therapy,  etiology*
Ochronosis / complications*,  diagnosis*
Prednisolone / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Gout Suppressants; 315-30-0/Allopurinol; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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