Document Detail


A case of obstructive jaundice due to autoimmune pancreatitis and a review of the literature.
MedLine Citation:
PMID:  24482076     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A 33-year-old man presented with jaundice, mild pancreatitis, and some weight loss. Laboratory tests showed cholestatic icterus. Imaging revealed distal bile duct obstruction and a mass in the head of the pancreas suspicious for cancer. Besides the enlargement of the head, the whole pancreatic parenchyma was altered. Therefore, autoimmune pancreatitis was considered. Endoscopic ultrasound biopsy found pancreatic tissue with lymphoplasmacytic inflammation and fibrosis. IgG4 serum concentration was within normal range. Due to the benign histology, a therapeutic attempt with prednisolone was initiated. The radiologic changes improved within 2 weeks, which supported the diagnosis of autoimmune pancreatitis. Bile duct obstruction and radiologic abnormalities of the pancreas completely resolved after a 4-month course of steroid treatment. Within 10 months, no relapse occurred. In context with this case, the recent literature was reviewed and the international consensus diagnostic criteria for autoimmune pancreatitis are summarized.
Authors:
Friedrich Wewalka; Alexander Ziachehabi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-1-31
Journal Detail:
Title:  Wiener medizinische Wochenschrift (1946)     Volume:  -     ISSN:  1563-258X     ISO Abbreviation:  Wien Med Wochenschr     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-1-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708475     Medline TA:  Wien Med Wochenschr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Vernacular Title:
Fallbericht eines Verschlussikterus durch Autoimmunpankreatitis und Überblick der aktuellen Literatur.
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