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A case of mixed connective tissue disease presenting with nephrotic syndrome.
MedLine Citation:
PMID:  17143681     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A 70-year-old woman was admitted to our hospital for the treatment of diffuse scleroderma and marked edema in the lower extremities. Renal biopsy revealed membranous change, interstitial nephritis, and intimal hyperplasia of the small arteries. The patient was diagnosed as having mixed connective tissue disease (MCTD) presenting with nephrotic syndrome (NS). She responded well to a combination treatment consisting of methylprednisolone (m-PSL) pulse therapy, oral PSL, and cyclosporine A (CsA). We speculated on the actual pathogenesis of NS in this case of MCTD.
Authors:
Hiro Kuroda; Keita Ishii; Yuji Negoro; Hiroko Sugiyama; Junko Inoue; Chiga Ogurusu; Takeshi Kikuchi; Keisei Shimoe; Katsutoshi Sunami
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Modern rheumatology / the Japan Rheumatism Association     Volume:  14     ISSN:  1439-7595     ISO Abbreviation:  Mod Rheumatol     Publication Date:  2004  
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-07-11     Revised Date:  2007-08-01    
Medline Journal Info:
Nlm Unique ID:  100959226     Medline TA:  Mod Rheumatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  236-40     Citation Subset:  -    
Affiliation:
Department of Internal Medicine, Chugoku Central Hospital of the Mutual Aid Association of Public School Teachers, 6-3-1 Nishifukatsu-cho, Fukuyama 721-8581, Japan. h-kuroda@fukuyama.hiroshima.med.or.jp
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