Document Detail


A case of microscopic polyangiitis with skin manifestations in a seven-year-old girl.
MedLine Citation:
PMID:  24050297     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A case of a 7-year-old girl with microscopic polyangiitis (MPA) with a skin eruption characterized by maculopapular, erythematous and purpuric lesions on the face, elbows, and knees is presented. Anti-neutrophil cytoplasmic autoantibodies (ANCA) with myeloperoxidase specificity (MPO-ANCA) were identified. Chest X-ray and computed tomography scan revealed diffuse infiltrates in both lung fields, suggesting alveolar hemorrhage. Microscopic hematuria was detected but a renal biopsy showed no abnormalities. Histological examination of a skin biopsy from a purpuric papule showed leukocytoclastic vasculitis of the small vessels in the entire dermis. The patient was treated with prednisolone and mizoribine, resulting in an improvement in the skin lesions except for those on the knee.
Authors:
Yozo Yamada; Chie Kitagawa; Ichiro Kamioka; Ko-Ron Chen; Masahiro Oka
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Publication Detail:
Type:  Journal Article     Date:  2013-09-14
Journal Detail:
Title:  Dermatology online journal     Volume:  19     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2013  
Date Detail:
Created Date:  2013-09-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  19624     Citation Subset:  IM    
Affiliation:
Kakogawa West Hospital.
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