Document Detail

A case of metastatic squamous cell carcinoma of the hypopharynx manifesting as acute abdomen.
MedLine Citation:
PMID:  15175779     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Squamous cell head and neck cancers are usually confined to local and regional sites but occasionally, patients may present with rare manifestations of distant metastases. CLINICAL PICTURE: A 23-year-old female was treated with concurrent chemo-radiotherapy for stage IVA post-cricoid squamous cell carcinoma. A month later, she presented with acute abdomen and was found to have extensive peritoneal nodules at laparotomy. Intestinal obstruction soon followed. TREATMENT: She was managed conservatively for the intestinal obstruction and given weekly paclitaxel. OUTCOME: She continued to deteriorate and succumbed shortly after the diagnosis of carcinomatosis peritoneii. CONCLUSION: This rare and aggressive presentation reminds us to be cognizant of relapsed head and neck cancers manifesting atypically, and the need for more aggressive search of distant disease in at least some subgroups of head and neck cancer.
Z W Wong; S S Leong; T Tan; K Mancer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  33     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-06-03     Completed Date:  2004-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  356-8     Citation Subset:  IM    
Department of Medical Oncology, National Cancer Centre, Singapore.
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MeSH Terms
Abdomen, Acute / etiology*
Carcinoma, Squamous Cell / diagnosis,  secondary*
Hypopharyngeal Neoplasms / pathology*
Intestinal Obstruction / etiology
Peritoneal Neoplasms / complications,  diagnosis,  secondary*

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