Document Detail


A case of lower extremity venous thrombosis in the pediatric emergency department: associations with May-Thurner syndrome and isotretinoin use.
MedLine Citation:
PMID:  21293221     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Unilateral calf swelling and pain is not a common complaint in the pediatric emergency department. We present a case of a 17-year-old adolescent boy with no past medical history who presented with left leg swelling and pain while taking prednisone and isotretinoin. He was found to have an extensive occlusive thrombus throughout the deep venous system in his left leg. He was later diagnosed with May-Thurner syndrome, an anatomic variant in which the right iliac artery compresses the left iliac vein. We review the differential diagnosis, diagnostic workup, and initial ED management of deep venous thrombosis and provide a brief discussion of May-Thurner syndrome and the association of isotretinoin and vascular thrombi.
Authors:
Mary C Whitman; David M Walker
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric emergency care     Volume:  27     ISSN:  1535-1815     ISO Abbreviation:  Pediatr Emerg Care     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-04     Completed Date:  2011-06-17     Revised Date:  2012-02-02    
Medline Journal Info:
Nlm Unique ID:  8507560     Medline TA:  Pediatr Emerg Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  125-8     Citation Subset:  IM    
Affiliation:
Yale University School of Medicine, New Haven, CT, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Angioplasty / instrumentation,  methods
Anticoagulants / therapeutic use
Emergency Service, Hospital
Follow-Up Studies
Heparin / therapeutic use
Humans
Iliac Artery / abnormalities*,  radiography
Iliac Vein / abnormalities*,  radiography
Isotretinoin / administration & dosage,  adverse effects
Male
Peripheral Arterial Disease / complications*,  radiography
Phlebography
Pulmonary Embolism / drug therapy,  etiology*,  radiography
Risk Assessment
Stents
Steroids / administration & dosage,  adverse effects
Syndrome
Vascular Malformations / complications*,  radiography
Venous Thrombosis / etiology*,  physiopathology,  surgery
Grant Support
ID/Acronym/Agency:
GM07205/GM/NIGMS NIH HHS; T32 GM007205-24/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Steroids; 4759-48-2/Isotretinoin; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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