| A case of Lewis-Sumner syndrome showing dramatic improvement after plasma exchange. | |
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MedLine Citation:
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PMID: 20592909 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a patient with Lewis-Sumner syndrome (LSS) who showed an improvement only with plasma exchange (PE). The patient, 32-yr old man, had progressive multifocal motor-sensory deficits with persistent, multiple conduction blocks and marked slowing of NCVs. Nerve pathology supported a diagnosis of demyelinating neuropathy by revealing marked loss of myelinated fibers with inter- and intrafascicular variation. Although the patient was refractory to treatment with corticosteroid and intravenous immunoglobulin, PE produced a dramatic improvement. Our experience strongly proposes that PE should be tried for refractory LSS. |
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Authors:
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Young-Eun Park; Ji-Won Yook; Dae-Seong Kim |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-06-16 |
Journal Detail:
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Title: Journal of Korean medical science Volume: 25 ISSN: 1598-6357 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-01 Completed Date: 2010-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 1101-4 Citation Subset: IM |
Affiliation:
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Department of Neurology, Pusan National University School of Medicine, Busan, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use Adult Demyelinating Diseases / diagnosis*, pathology, physiopathology, therapy* Humans Immunoglobulins, Intravenous / therapeutic use Male Neural Conduction / physiology Peripheral Nerves / pathology, physiopathology Plasma Exchange* Syndrome Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Immunoglobulins, Intravenous |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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