Document Detail

A case of isolated neurosarcoidosis associated with psychosis.
MedLine Citation:
PMID:  23291801     Owner:  NLM     Status:  In-Data-Review    
Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Isolated neurosarcoidosis without signs of systemic involvement has rarely been reported in the literature. We report a case of isolated neurosarcoidosis that presented with psychiatric symptoms and headache. Cranial MRI revealed bilateral diffuse high intensity lesions in the deep white matter, with a linear contrast enhancement of perivascular areas. Histological examination of a stereotactic brain biopsy specimen demonstrated noncaseating granulomas. Further research did not reveal any evidence of systemic disease. The patient was treated with corticosteroids and responded well to medical therapy. The diagnosis of isolated neurosarcoidosis is a challenge and may require histological examination.
Arif Celebi; Sule Deveci; Azize E Gursoy; Mehmet Kolukisa
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurosciences (Riyadh, Saudi Arabia)     Volume:  18     ISSN:  1319-6138     ISO Abbreviation:  Neurosciences (Riyadh)     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101252453     Medline TA:  Neurosciences (Riyadh)     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  70-3     Citation Subset:  IM    
Department of Neurology, Medical Faculty, Bezmialem Vakif University, Fatih, Istanbul 34093, Turkey. Tel. +902 (1) 25233816. Fax. +902 (1) 25346970. E-mail:
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