| A case of isolated light chain deposition disease in the duodenum. | |
| | |
MedLine Citation:
|
PMID: 22323870 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Light chain deposition disease (LCDD) is a rare disorder associated with a clonal proliferation of plasma cells, which synthesize abnormal monoclonal immunoglobulin light chains. LCDD is characterized by systemic deposition of light chains in various organs, with the kidneys being most commonly affected. There have been few reports of isolated LCDD. We report a rare case of LCDD limited to a duodenal polyp. A 63-yr-old man visited our hospital for health screening without symptoms in 2009. On gastrofiberscopy, a duodenal polyp was observed. The biopsy showed diffuse infiltration by atypical plasma cells, which were positive for kappa-type light chains by immunohistochemistry. While the patient refused further management, we could find no evidence of recurrence until 2 yr after the initial diagnosis. It has been reported that isolated LCDD has relatively good prognosis compared to systemic LCDD. However, treatment for this disease has not been established yet. |
| | |
Authors:
|
Hee-Jun Kim; Eunkyung Park; Tae Jin Lee; Jae Hyuk Do; Young Joo Cha; Sang Jae Lee |
Publication Detail:
|
Type: Journal Article Date: 2012-01-27 |
Journal Detail:
|
Title: Journal of Korean medical science Volume: 27 ISSN: 1598-6357 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-02-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: Korea (South) |
Other Details:
|
Languages: eng Pagination: 207-10 Citation Subset: IM |
Affiliation:
|
Division of Hemato-Oncology, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Oral solubilized ursodeoxycholic Acid therapy in amyotrophic lateral sclerosis: a randomized cross-o...
Next Document: Unilateral Pulmonary Edema: A Rare Initial Presentation of Cardiogenic Shock due to Acute Myocardial...