Document Detail


A case of intravascular lymphoma with mixed lineage antigen expression in a cat.
MedLine Citation:
PMID:  18045342     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 3-year-old neutered male British shorthair cat was presented to the Clinic for Small Animal Medicine, Internal Medicine and Clinical Pathology, at the Justus-Liebig-University Giessen with a short history of lethargy, severe dyspnoea, fever, anaemia, thrombocytopenia and hyperbilirubinaemia. In blood smears and lymph node aspirates, large pleomorphic lymphatic blasts were detected. On necropsy splenic infarcts and moderate hydrothorax as well as moderate ascites could be observed. Histological examination revealed large numbers of lymphoid blasts within the lumen of the vessels of the lung, lymph nodes, the liver, the chorioid coat of the eyes, in meningeal vessels, arteries and veins of the brain, and within the larger splenic vessels. Neoplastic cells immunohistochemically stained positive for CD45R and CD3. Based on these findings, an intravascular lymphoma was diagnosed.
Authors:
M Henrich; M Huisinga; N Bauer; M Reinacher
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine     Volume:  54     ISSN:  0931-184X     ISO Abbreviation:  J Vet Med A Physiol Pathol Clin Med     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-29     Completed Date:  2008-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100955112     Medline TA:  J Vet Med A Physiol Pathol Clin Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  575-8     Citation Subset:  IM    
Affiliation:
Institute for Veterinary Pathology, Justus-Liebig-University Giessen, Giessen, Germany. manfred.henrich@vetmed.uni-giessen.de
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MeSH Terms
Descriptor/Qualifier:
Animals
Antigens, Differentiation, B-Lymphocyte / metabolism
Antigens, Differentiation, T-Lymphocyte / metabolism
Cat Diseases / genetics,  immunology,  pathology*
Cats
Cell Differentiation
Fatal Outcome
Gene Expression Profiling
Lymphoma / genetics,  immunology,  pathology,  veterinary*
Male
Chemical
Reg. No./Substance:
0/Antigens, Differentiation, B-Lymphocyte; 0/Antigens, Differentiation, T-Lymphocyte

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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