Document Detail

A case of idiopathic nodular glomerulosclerosis mimicking diabetic glomerulosclerosis (Kimmelstiel-Wilson type).
MedLine Citation:
PMID:  12092775     Owner:  NLM     Status:  MEDLINE    
A case of idiopathic nodular glomerulosclerosis mimicking diabetic Kimmelstiel-Wilson glomerulopathy is reported. The patient was a 45-year-old man suffering from nephrotic syndrome. Light and electron microscopy revealed diffuse and nodular glomerulosclerosis indistinguishable from diabetic nodular glomerulosclerosis. Diabetes mellitus, however, had been excluded both by extensive clinical and by laboratory investigation. The differential diagnosis also included amyloidotic and non-amyloidotic fibrillary glomerulopathy, light chain glomerulopathy, collagen type III disease, immunotactoid glomerulopathy, and the sclerosing variant of membranoproliferative glomerulonephritis. Immunohistochemistry and ultrastructural investigations, however, excluded these entities, and the diagnosis of idiopathic nodular glomerulosclerosis was made. This variant has to be included in the differential diagnosis of nodular glomerulopathy associated with nephrotic syndrome.
J Müller-Höcker; M Weiss; G H Thoenes; A Grund; A Nerlich
Related Documents :
2140085 - Effect of initiation of insulin therapy on t-lymphocyte activation in type 1 diabetes.
2129025 - Comparison of secondary failure rate between three second generation sulphonylureas.
15527035 - Classification of mca stenosis in diabetes by mlp and rbf neural network.
7739375 - Mri evaluation of diabetic muscle infarction.
15337505 - Tranilast reduces mesenteric vascular collagen deposition and chymase-positive mast cel...
7189165 - Diurnal changes in plasma lipoproteins in normal subjects and diabetics.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology, research and practice     Volume:  198     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  2002  
Date Detail:
Created Date:  2002-07-02     Completed Date:  2002-12-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  375-9     Citation Subset:  IM    
Pathologisches Institut, Ludwig-Maximilians-Universität, Munich, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amyloidosis / pathology
Collagen Diseases / pathology
Collagen Type III
Diabetic Nephropathies / metabolism,  pathology*
Diagnosis, Differential
Fluorescent Antibody Technique, Indirect
Glomerular Mesangium / ultrastructure
Glomerulonephritis / pathology
Glomerulonephritis, Membranous / pathology
Glomerulosclerosis, Focal Segmental / metabolism,  pathology*
Kidney Glomerulus / pathology
Middle Aged
Reg. No./Substance:
0/Collagen Type III

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Primary bony peripheral T-cell lymphoma mimicking nasal type NK/T-cell lymphoma: a case report.
Next Document:  Seasonal abundance of adult ixodid ticks infesting cattle belonging to resource-limited farmers in t...