Document Detail


A case of human pregnancy after microinjection of capacitated sperm into the perivitelline space.
MedLine Citation:
PMID:  1753169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Microinjection of capacitated sperm into the perivitelline space of oocyte was offered to one couple with persistent infertility of mixed origin. The husband's semen was subnormal, whereas his wife had definitive tubal occlusion and polycystic ovaries. Four previous in vitro fertilization (IVF) attempts were performed but no fertilization was obtained. After superovulation, 13 oocytes were collected. Ten were submitted to microinjection and two were damaged during the procedure. One of the remaining eight had two pronuclei 18 hr after microinjection and progressed to a four-cell embryo after 48 hr. After reimplantation, a normal pregnancy was initiated, caryotype (46XX) was checked at 17 weeks. A normal and healthy girl has been delivered at term.
Authors:
C Wittemer; L Moreau; P Dellenbach; P Gerlinger; M A Le Meur; P Chambon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of in vitro fertilization and embryo transfer : IVF     Volume:  8     ISSN:  0740-7769     ISO Abbreviation:  J In Vitro Fert Embryo Transf     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1992-01-30     Completed Date:  1992-01-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8412594     Medline TA:  J In Vitro Fert Embryo Transf     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  222-4     Citation Subset:  IM    
Affiliation:
Département de Fécondation in vitro, CMCO BP120, Schiltigheim, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Embryo Transfer
Female
Fertilization in Vitro / methods*
Humans
Male
Microinjections / methods*
Oocytes*
Sperm Capacitation
Sperm-Ovum Interactions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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