Document Detail

A case of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease) with dystrophic calcinosis cutis and retinal lesions.
MedLine Citation:
PMID:  12227486     Owner:  NLM     Status:  MEDLINE    
A 65-year-old Japanese female developed a nodule on the distal interphalangealjoint of her right thumb. She also had multiple telangiectasias on her face, oral mucosa, tongue, nasal mucosa and upper extremities. A lip biopsy showed irregularly dilated capillaries and venules lined by flat endothelial cells. The nodule in the right thumb was resected. Histopathology revealed calcium deposits in the dermis. This case was diagnosed as dystrophic calcinosis cutis within hereditary hemorrhagic telangiectasia. Ophthalmologic examination showed bilateral retinal vascular lesions with dilated and tortuous retinal venules.
Hideto Takahama; Shigemitsu Noto; Masaru Ito; Hiroyuki Nishimoto; Mamoru Tadokoro
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  29     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-09-13     Completed Date:  2002-10-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  512-5     Citation Subset:  IM    
Division of Dermatology, Sagamihara-kyodo Hospital, Sagamihara-shi, Japan.
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MeSH Terms
Calcinosis / complications*,  pathology
Retinal Diseases / complications*,  pathology
Retinal Vessels / pathology
Skin Diseases / complications*,  pathology
Telangiectasia, Hereditary Hemorrhagic / complications*

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