| [A case of glucose-sensitive insulinoma accompanied by slightly elevated serum insulin levels and persisting convulsions after the surgically removed neuroendocrine tumor]. | |
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MedLine Citation:
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PMID: 23291205 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Insul(in)oma is a usually solitary or, in some cases, multifocal tumor of pancreatic beta cells. It may be a component of multiple endocrine neoplasia type 1. or von Hippel-Lindau syndrome. In typical forms the diagnosis - based on the Whipple triad - is simple, however, it may be difficult to recognize in cases with near normal or only slightly elevated serum insulin levels, as well as in patients with known convulsive episodes. With the case presentation of an 81-year-old woman the authors draw attention to the pitfalls of the correct diagnosis. A special feature of the presented case is that convulsions persisted after surgical removal of the pancreatic neuroendocrine tumor verified with functional and imaging methods. Recurrant or residual tumor was not found, and morphological damage of the brain was absent. In the background of the continuing convulsions cerebrovascular alterations as well as the cytotoxic effect of the hypoglycemia-induced excessive glutamate production can be postulated. Orv. Hetil., 2013, 154, 69-73. |
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Authors:
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Zsuzsanna Soós; Anna Czégeni; Ferenc Salamon; Mónika Salamon; István Kenessey; András Folyovich; Tibor Tihanyi; Gábor Winkler |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Orvosi hetilap Volume: 154 ISSN: 0030-6002 ISO Abbreviation: Orv Hetil Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-01-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376412 Medline TA: Orv Hetil Country: Hungary |
Other Details:
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Languages: hun Pagination: 69-73 Citation Subset: IM |
Affiliation:
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Szent János Kórház II. Belgyógyászat-Diabetológia Budapest Diós árok 1-3. 1125. |
Vernacular Title:
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Glükózszenzitív insulinoma mérsékelten emelkedett széruminzulinszinttel, eltávolítása után is fennmaradó epilepsziás rohamokkal. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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