Document Detail


A case of giant cell interstitial pneumonia.
MedLine Citation:
PMID:  2717833     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report is of a case of giant cell interstitial pneumonia (GIP) diagnosed by transbronchial lung biopsy (TBLB) and treated effectively with corticosteroid. The patient was a 61-year-old man with cough, dyspnea and findings of diffuse reticular opacities on chest X-ray. In the microscopic section of a biopsied specimen, varied forms of giant cells were observed, some with a cannibalistic appearance. Numerous giant cells and some lymphocytes were also observed in the bronchoalveolar lavage fluid. The possibility of measles pneumonia was ruled out by a negative serum antibody test and the absence of inclusion bodies in the giant cells. The patient had neither a past history of exposure to heavy metals nor to organic dusts. A distinct improvement was obtained with 30 mg of prednisolone administered daily for two weeks and then tapered off gradually.
Authors:
N Miyazaki; M Kido; A Kajiki; Y Morimoto
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of UOEH     Volume:  11     ISSN:  0387-821X     ISO Abbreviation:  J. UOEH     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-06-22     Completed Date:  1989-06-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909645     Medline TA:  J UOEH     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  63-7     Citation Subset:  IM    
Affiliation:
Pulmonary Division, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
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MeSH Terms
Descriptor/Qualifier:
Biopsy / methods
Bronchoalveolar Lavage Fluid / pathology
Humans
Lung / pathology
Lymphocytes / pathology
Male
Middle Aged
Prednisolone / therapeutic use
Pulmonary Fibrosis / drug therapy,  pathology*
Chemical
Reg. No./Substance:
50-24-8/Prednisolone

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