Document Detail


A case of gastric adenocarcinoma associated with giant-cell phlebitis.
MedLine Citation:
PMID:  14666610     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 60-year-old male patient with advanced gastric adenocarcinoma was treated by subtotal gastrectomy with dissection of the regional lymph nodes. Microscopic examination of the tumour revealed tubular adenocarcinoma which invaded the muscularis propria. There was no evidence of metastatic carcinoma in the dissected lymph nodes (pT2N0Mx). Granulomatous reaction comprising epithelioid cells and giant cells involved subserosal muscular veins, adjacent to the carcinoma tissue. Fibrinoid necrosis, with or without infiltration of eosinophils, was noted within the lumen of some veins. The acid-fast and fungal stains were negative. Remnants of parasites were not identified in serial sections of the paraffin blocks. No pulmonary disease was evident on radiographic or pulmonary examination. The presence of granulomatous destruction of muscular veins with sparing of arteries suggested the diagnosis of giant-cell phlebitis. To our knowledge, there have been no previous reports regarding an association between giant-cell phlebitis and advanced gastric adenocarcinoma.
Authors:
Rosario A Caruso; Antonino Parisi; Fabiano Valerio; Patrizia Napoli; Giovanni Parisi
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  23     ISSN:  0250-7005     ISO Abbreviation:  Anticancer Res.     Publication Date:    2003 Sep-Oct
Date Detail:
Created Date:  2003-12-11     Completed Date:  2003-12-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  4109-12     Citation Subset:  IM    
Affiliation:
Dipartimento di Patologia Umana pad D, Policlinico Universitario, I-98125 Messina, Italy. rosariocaruso@tin.it
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / blood supply,  complications*,  pathology
Humans
Male
Middle Aged
Phlebitis / complications*,  pathology
Stomach Neoplasms / blood supply,  complications*,  pathology

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