Document Detail


A case of esophageal cancer showing complete remission of nephrotic syndrome after esophagectomy.
MedLine Citation:
PMID:  20944166     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nephrotic syndrome associated with a malignant tumor may remit following resection of the tumor. This report documents a case of esophageal cancer with concurrent nephrotic syndrome in which a surgical resection of the tumor resulted in a complete remission of nephrotic syndrome. A 78-year-old male patient noticed edema of his lower legs in February 2009 and was diagnosed with nephrotic syndrome. An endoscopic examination revealed an indented lesion with a nearly semiannular low elevation on the posterior wall of the esophagus at 31 to 34 cm from the upper incisors, and a diagnosis of esophageal cancer was made. A two-stage operation was planned. In March 2009, a subtotal resection of the thoracic esophagus through a right thoracic approach and cervical external esophagostomy were performed, and in April 2009, antethoracic route esophagogastrostomy was performed. The urinary protein levels were negative by the 86th day of hospitalization, and the patient progressively improved and was discharged on the 91st hospital day. There has been no recurrence of esophageal cancer or relapse of nephrotic syndrome at 12 months following the operation. In esophageal cancer patients with nephrotic syndrome, surgical treatment should be undertaken because the remission of nephrotic syndrome may be expected following tumor resection. For this purpose, selecting the appropriate operative procedures and careful perioperative management, including nutritional management, are of profound importance.
Authors:
Yoshihiko Naritaka; Shinichi Asaka; Akira Miyaki; Noriyuki Isohata; Takeshi Shimakawa; Kentaro Yamaguchi; Takao Katsube; Toko Muraoka; Shunichi Shiozawa; Kazuhiko Yoshimatsu; Kenji Ogawa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  30     ISSN:  1791-7530     ISO Abbreviation:  Anticancer Res.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-14     Completed Date:  2010-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  3763-7     Citation Subset:  IM    
Affiliation:
Department of Surgery, Tokyo Women's Medical University Medical Center East, 2-1-10 Nishiogu Arakawa-ku, Tokyo 116-8567, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Carcinoma, Squamous Cell / complications*,  pathology,  surgery*
Esophageal Neoplasms / complications*,  pathology,  surgery*
Esophagectomy
Humans
Male
Neoplasm Staging
Nephrotic Syndrome / etiology*
Remission Induction

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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