| A case of erythromelalgia: good response to treatment with gabapentin. | |
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MedLine Citation:
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PMID: 20480803 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Erythromelalgia is a rare chronic disorder characterized by intense burning pain, redness, swelling and increased skin temperature. It occurs primarily in the feet, but may also involve the hands, face and ears. Warming of the extremity or placing and maintaining the extremity in a dependent position can exacerbate symptoms. These symptoms are typically refractory to various medications, but are relieved by elevation or exposure to cold. Although a specific therapy is not available for erythromelalgia yet, several treatment modalities may be used as therapeutic options, including: aspirin, indomethacine beta-blockers, calcium channel antagonists, misoprostol, diltiazem, tricyclic antidepressants, serotonin reuptake inhibitors and number of more aggressive procedures--such as intravenous lidocaine, epidural anaesthesia, intrathecal opiates and sympathetic ganglion blockade. There are very few reports in the literature of gabapentin successfully treating erythromelalgia. Here, the authors report a case of primary erythromelalgia in a 20-year-old woman responding to gabapentin therapy. |
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Authors:
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Ali Murat Ceyhan; Ipek Gurses; Mehmet Yildirim; Vahide Baysal Akkaya |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of drugs in dermatology : JDD Volume: 9 ISSN: 1545-9616 ISO Abbreviation: J Drugs Dermatol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-19 Completed Date: 2010-06-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101160020 Medline TA: J Drugs Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 565-7 Citation Subset: IM |
Affiliation:
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Suleyman Demirel University, School of Medicine, Department of Dermatology, Isparta, Turkey. amuratceyhan@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amines
/
adverse effects,
therapeutic use* Analgesics / adverse effects, therapeutic use* Cyclohexanecarboxylic Acids / adverse effects, therapeutic use* Erythromelalgia / drug therapy*, physiopathology Female Follow-Up Studies Humans Treatment Outcome Young Adult gamma-Aminobutyric Acid / adverse effects, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Amines; 0/Analgesics; 0/Cyclohexanecarboxylic Acids; 56-12-2/gamma-Aminobutyric Acid; 60142-96-3/gabapentin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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