Document Detail

A case of erythromelalgia: good response to treatment with gabapentin.
MedLine Citation:
PMID:  20480803     Owner:  NLM     Status:  MEDLINE    
Erythromelalgia is a rare chronic disorder characterized by intense burning pain, redness, swelling and increased skin temperature. It occurs primarily in the feet, but may also involve the hands, face and ears. Warming of the extremity or placing and maintaining the extremity in a dependent position can exacerbate symptoms. These symptoms are typically refractory to various medications, but are relieved by elevation or exposure to cold. Although a specific therapy is not available for erythromelalgia yet, several treatment modalities may be used as therapeutic options, including: aspirin, indomethacine beta-blockers, calcium channel antagonists, misoprostol, diltiazem, tricyclic antidepressants, serotonin reuptake inhibitors and number of more aggressive procedures--such as intravenous lidocaine, epidural anaesthesia, intrathecal opiates and sympathetic ganglion blockade. There are very few reports in the literature of gabapentin successfully treating erythromelalgia. Here, the authors report a case of primary erythromelalgia in a 20-year-old woman responding to gabapentin therapy.
Ali Murat Ceyhan; Ipek Gurses; Mehmet Yildirim; Vahide Baysal Akkaya
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  9     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-19     Completed Date:  2010-06-08     Revised Date:  2013-06-11    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  565-7     Citation Subset:  IM    
Suleyman Demirel University, School of Medicine, Department of Dermatology, Isparta, Turkey.
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MeSH Terms
Amines / adverse effects,  therapeutic use*
Analgesics / adverse effects,  therapeutic use*
Cyclohexanecarboxylic Acids / adverse effects,  therapeutic use*
Erythromelalgia / drug therapy*,  physiopathology
Follow-Up Studies
Treatment Outcome
Young Adult
gamma-Aminobutyric Acid / adverse effects,  therapeutic use*
Reg. No./Substance:
0/Amines; 0/Analgesics; 0/Cyclohexanecarboxylic Acids; 56-12-2/gamma-Aminobutyric Acid; 6CW7F3G59X/gabapentin

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