Document Detail

A case of erythroleukaemia with homogeneously staining regions on chromosomes.
MedLine Citation:
PMID:  6582342     Owner:  NLM     Status:  MEDLINE    
A case of erythroleukaemia with homogeneously staining regions on chromosomes is described. The number of chromosomes in bone marrow cells varied from 41 to 46 with a mode of 43. A variety of structural and numerical chromosomal abnormalities was observed. Two marker chromosomes with homogeneously staining regions were found in all aneuploid cells examined. Intensive chemotherapy failed to induce a remission and the patient died 3.9 months after diagnosis. The relation of the homogeneously staining regions on chromosomes to the two courses of chemotherapy prior to cytogenetic study is discussed.
Y S Li; G Khalid; J G Matthews; F G Hayhoe
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Leukemia research     Volume:  7     ISSN:  0145-2126     ISO Abbreviation:  Leuk. Res.     Publication Date:  1983  
Date Detail:
Created Date:  1984-03-22     Completed Date:  1984-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7706787     Medline TA:  Leuk Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  755-9     Citation Subset:  IM    
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Marrow / ultrastructure*
Chromosome Aberrations*
Chromosome Banding
Leukemia, Erythroblastic, Acute / drug therapy,  ultrastructure*
Leukopenia / chemically induced

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