Document Detail


A case of erythroleukaemia with homogeneously staining regions on chromosomes.
MedLine Citation:
PMID:  6582342     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of erythroleukaemia with homogeneously staining regions on chromosomes is described. The number of chromosomes in bone marrow cells varied from 41 to 46 with a mode of 43. A variety of structural and numerical chromosomal abnormalities was observed. Two marker chromosomes with homogeneously staining regions were found in all aneuploid cells examined. Intensive chemotherapy failed to induce a remission and the patient died 3.9 months after diagnosis. The relation of the homogeneously staining regions on chromosomes to the two courses of chemotherapy prior to cytogenetic study is discussed.
Authors:
Y S Li; G Khalid; J G Matthews; F G Hayhoe
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Leukemia research     Volume:  7     ISSN:  0145-2126     ISO Abbreviation:  Leuk. Res.     Publication Date:  1983  
Date Detail:
Created Date:  1984-03-22     Completed Date:  1984-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7706787     Medline TA:  Leuk Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  755-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Aneuploidy
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Marrow / ultrastructure*
Chromosome Aberrations*
Chromosome Banding
Humans
Leukemia, Erythroblastic, Acute / drug therapy,  ultrastructure*
Leukopenia / chemically induced
Male
Metaphase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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