| A case of delirium, motor disturbances, and autonomic dysfunction due to baclofen and tizanidine withdrawal: a review of the literature. | |
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MedLine Citation:
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PMID: 21353141 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We report a case of delirium accompanied by extrapyramidal symptoms and autonomic dysfunction in a 59-year-old man following abrupt cessation of baclofen and tizanidine. An extensive search for the etiology was undertaken, but it was only after a careful history was taken that suspicion for baclofen and tizanidine withdrawal was raised. The delirium and motor disturbances resolved within 24 h of reintroduction of baclofen. Withdrawal from muscle relaxants requires a high index of suspicion but should be considered in patients who manifest signs and symptoms of withdrawal from the medications, particularly visual hallucinations, rigidity and autonomic dysfunction. |
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Authors:
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David E Karol; Andrew J Muzyk; Xavier A Preud'homme |
Publication Detail:
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Type: Journal Article Date: 2010-11-13 |
Journal Detail:
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Title: General hospital psychiatry Volume: 33 ISSN: 1873-7714 ISO Abbreviation: Gen Hosp Psychiatry Publication Date: 2011 Jan-Feb |
Date Detail:
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Created Date: 2011-02-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905527 Medline TA: Gen Hosp Psychiatry Country: United States |
Other Details:
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Languages: eng Pagination: 84.e1-2 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Duke University Medical Center, Durham, NC 27705, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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