Document Detail

A case-control study of polymorphic eruption of pregnancy.
MedLine Citation:
PMID:  17884242     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Polymorphic eruption of pregnancy (PEP) is a pruritic disease that usually occurs in primiparous women, most commonly in the last trimester of pregnancy. The origin and pathomechanisms still remain unknown. OBJECTIVES: We attempted to determine the parameters that may be associated with or complicate the course of PEP. METHODS: Data of 200 pregnant women (40 PEP and 160 control) were studied retrospectively and compared statistically using univariable and multivariable analysis. RESULTS: In multivariate analysis, pregnancy with male fetuses (P = .02) and delivery by cesarean section (P = .012) were overrepresented in the PEP group. A tendency toward more multiple gestation pregnancy in PEP was found (P = .07). The risk of PEP was not related to excessive maternal or fetal weight gain. LIMITATIONS: This was a retrospective study. CONCLUSION: This large case-control study confirms the already suspected association of PEP with male fetuses and cesarean deliveries in multivariate analysis. The higher rate of multiple gestation pregnancy was also established.
Stephanie Regnier; Virginie Fermand; Pierre Levy; Serge Uzan; Selim Aractingi
Publication Detail:
Type:  Journal Article     Date:  2007-09-19
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  58     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-26     Completed Date:  2008-01-09     Revised Date:  2008-09-30    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  63-7     Citation Subset:  IM    
Department of Dermatology, Hôpital Tenon (Assistance Publique-Hôpitaux de Paris), Unité de Formation et de Recherche Pierre et Marie Curie, Paris 6, Université Pierre et Marie Curie, Paris, France.
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MeSH Terms
Case-Control Studies
Cesarean Section / statistics & numerical data
Hospitalization / statistics & numerical data
Multivariate Analysis
Pregnancy Complications / epidemiology*
Pregnancy, Multiple / statistics & numerical data
Pruritus / epidemiology*
Retrospective Studies
Comment In:
J Am Acad Dermatol. 2008 Oct;59(4):722-3   [PMID:  18793946 ]

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