| A case-control study of maternal alcohol consumption and intrauterine growth retardation. | |
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MedLine Citation:
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PMID: 11557182 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Heavy maternal drinking during pregnancy causes fetal alcohol syndrome, but whether more moderate alcohol consumption is associated with such adverse pregnancy outcomes as intrauterine growth retardation (IUGR) remains controversial. METHODS: Using data from a case-control study, we examined the association between maternal alcohol consumption and risk for IUGR among 701 case and 336 control infants born during 1993-1995 in Monroe County, New York. RESULTS: Our results provide no evidence of an independent association between moderate maternal alcohol consumption (<14 drinks per week) and risk for IUGR. The risk for IUGR among heavy drinkers (> or =14 drinks per week) around the time of conception was OR = 1.4 (95% CI 0.7-2.6) for IUGR < or = 5th percentile and OR = 1.4 (95% CI 0.7-2.8) for IUGR 5th-10th percentile. For heavy drinkers during the first trimester, the OR was 1.3 (95% CI 0.4-4.5) for IUGR < or = 5th percentile and OR = 1.3 (95% CI 0.4-4.8) for IUGR 5th-10th percentile. CONCLUSIONS: Since IUGR is a heterogeneous outcome with a possible multifactorial origin, further studies are needed to examine the combined effects of alcohol and other environmental and genetic factors on IUGR risk for subgroups of IUGR. |
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Authors:
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Q Yang; B B Witkiewicz; R S Olney; Y Liu; M Davis; M J Khoury; A Correa; J D Erickson |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of epidemiology Volume: 11 ISSN: 1047-2797 ISO Abbreviation: Ann Epidemiol Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-09-14 Completed Date: 2001-10-04 Revised Date: 2008-06-23 |
Medline Journal Info:
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Nlm Unique ID: 9100013 Medline TA: Ann Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 497-503 Citation Subset: IM |
Affiliation:
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National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, MS F-45, Atlanta, GA 30341, USA |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohol Drinking / adverse effects, epidemiology* Case-Control Studies Female Fetal Growth Retardation / epidemiology*, etiology Humans Infant, Newborn Logistic Models Maternal Exposure* / adverse effects Pregnancy Risk |
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