Document Detail

A case-control study of cancer of the nose and paranasal sinuses and occupational exposures.
MedLine Citation:
PMID:  1442786     Owner:  NLM     Status:  MEDLINE    
The association between nasal cancer and various occupations was investigated in a case-control study in the provinces of Verona and Vicenza (northeastern Italy) and Siena (central Italy). Cases of malignant epithelial neoplasm of the nasal cavities and paranasal sinuses diagnosed in the years 1982-1987 in the hospitals of Verona, Legnago, Bussolengo, Vicenza, and Siena comprised the study. Controls were patients admitted to the same hospitals as the cases, with any diagnosis except chronic rhino-sinusal disease and nasal bleeding. Age, gender, residency, and date of admission were taken into account by matching. Cases and controls, or their next of kin, were interviewed or required to fill in a mailed questionnaire; the overall response rate was 70%. Altogether, 78 cases and 254 controls provided information on occupational history. Significantly increased risks were associated (in males) with work in the wood industry (odds ratio [O.R.]: 5.8; 90% confidence interval [C.I.]: (2.2-16) and in the leather industry (6.8; 1.9-25). Textile workers, furnacemen, construction workers, and workers with possible exposure to organic dusts showed increased risks even if statistical significance was not reached.
P Comba; G Battista; S Belli; B de Capua; E Merler; D Orsi; S Rodella; C Vindigni; O Axelson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of industrial medicine     Volume:  22     ISSN:  0271-3586     ISO Abbreviation:  Am. J. Ind. Med.     Publication Date:  1992  
Date Detail:
Created Date:  1992-12-04     Completed Date:  1992-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  511-20     Citation Subset:  IM    
Istituto Superiore di Sanità, Rome, Italy.
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MeSH Terms
Adenocarcinoma / epidemiology,  etiology
Air Pollutants, Occupational / adverse effects*
Carcinoma / epidemiology,  etiology
Carcinoma, Squamous Cell / epidemiology,  etiology
Case-Control Studies
Cross-Sectional Studies
Italy / epidemiology
Middle Aged
Nose Neoplasms / epidemiology*,  etiology
Occupational Diseases / epidemiology*,  etiology
Occupational Exposure / adverse effects,  statistics & numerical data*
Occupations / classification,  statistics & numerical data
Paranasal Sinus Neoplasms / epidemiology*,  etiology
Risk Factors
Reg. No./Substance:
0/Air Pollutants, Occupational

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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