Document Detail

A case-control study of baldness in relation to myocardial infarction in men.
MedLine Citation:
PMID:  8429606     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the relationship between male pattern baldness and the risk of myocardial infarction in men under the age of 55 years.
DESIGN AND PARTICIPANTS: A hospital-based, case-control study was conducted in eastern Massachusetts and Rhode Island. Cases were men admitted to a hospital for a first nonfatal myocardial infarction (n = 665); controls were men admitted to the same hospitals with noncardiac diagnoses (n = 772). Extent of baldness was assessed using the 12-point modified Hamilton Baldness Scale; other information was obtained by personal interview. Among the controls, the prevalence of any baldness was 34%, while the prevalence of baldness involving the vertex scalp was 23%.
RESULTS: After allowing for age, the relative risk estimate for frontal baldness compared with no hair loss was 0.9 (95% confidence interval, 0.6 to 1.3), for baldness involving the vertex scalp it was 1.4 (95% confidence interval, 1.2 to 1.9). Risk of myocardial infarction increased as the degree of vertex baldness increased (P < .01); for severe vertex baldness the relative risk was 3.4 (95% confidence interval, 1.7 to 7.0). The relationship between vertex baldness and myocardial infarction was consistent within strata defined by age and other risk factors for coronary artery disease.
CONCLUSION: These data support the hypothesis that male pattern baldness involving the vertex scalp is associated with coronary artery disease in men under the age of 55 years.
S M Lesko; L Rosenberg; S Shapiro
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JAMA     Volume:  269     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-03-10     Completed Date:  1993-03-10     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  998-1003     Citation Subset:  AIM; IM    
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MeSH Terms
Case-Control Studies
Confidence Intervals
Logistic Models
Middle Aged
Myocardial Infarction / epidemiology*
Odds Ratio
Risk Factors
Comment In:
JAMA. 1993 Jul 7;270(1):48   [PMID:  8510295 ]
JAMA. 1993 Feb 24;269(8):1035-6   [PMID:  8429586 ]
Erratum In:
JAMA 1993 May 19;269(19):2508

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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