| A case of concurrent sarcoidosis, aortitis syndrome and Crohn's disease. | |
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MedLine Citation:
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PMID: 22129508 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 24-year-old man was referred to our hospital due to bilateral hilar lymphadenopathy on chest radiography. He had been under medication for aortitis syndrome and Crohn's disease for 12 years. Surgical biopsy from the anterior segment of the left upper lobe and mediastinal lymph nodes was performed under video-assisted thoracoscopy. Histopathological examination revealed epithelioid cell granulomas without caseous necrosis, compatible with sarcoidosis. Full sequence analysis of the CARD15 gene, which is reportedly related to the formation of granulomatous lesions in Crohn's disease and sarcoidosis revealed no mutation of CARD15 gene. This is the first report of concurrent sarcoidosis, Crohn's disease and aortitis syndrome in an individual. |
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Authors:
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Koichi Izumikawa; Noriko Motoi; Hisashi Takaya; Atsushi Miyamoto; Yoshinobu Eishi; Kunihiko Yoshimura; Kazuma Kishi |
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Publication Detail:
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Type: Journal Article Date: 2011-12-01 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 50 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 2915-7 Citation Subset: IM |
Affiliation:
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Department of Respiratory Medicine, Respiratory Center, Toranomon Hospital, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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